• Little is known about the

  2022-07-06

  

  Little is known about the endocrinological control of reproduction in polychaetes. In vertebrates, gonadal maturation is regulated by the hypothalamo-pituitary-gonadal axis. GnRH, GTHs, and steroid hormones are involved in this axis (see Okubo and Nagahama, 2008). In two polychaete species, Perinere

• However Gingrich and Hen reported that absence

  2022-07-06

  

  However, Gingrich and Hen reported that absence of the gene at all stages of ontogenesis of mice may interfere with the normal developmental program and/or the organism may undergo changes in other systems to compensate for gene absence (46). In addition, potentially altered maternal behavior of GPR

• br Introduction Glucose is the major

  2022-07-06

  

  Introduction Glucose is the major carbon source in most organisms. Cancer Demethoxycurcumin receptor in particular require a steady source of energy to maintain growth and proliferation, and preferentially use glycolysis for their energy supply even under aerobic conditions. Glucose uptake in ma

• Despite their undisputed importance however FPR receptors

  2022-07-05

  

  Despite their undisputed importance, however, FPR receptors are not in the limelight of GPCR-related research (for review [12] and references therein). We, therefore, draw attention to this GPCR receptor family, in order to re-initiate FPR-related research, particularly in the light of biased agonis

• In the next set of experiments we sought to

  2022-07-05

  

  In the next set of experiments, we sought to determine the source of lysosomal 4EGI-1 inhibition by oxidative stress. Lysosomal exocytosis probably involves multiple steps including vesicle positioning, delivery, docking and fusion. The previous evidence and data in Fig. 1C,D show that TRPML1 is cri

• br Memories can last a

  2022-07-05

  

  Memories can last a lifetime, long after the transient events have passed. The fact that information stored in the VX-745 can outlast the environmental trigger implies that enduring cellular changes in the central nervous system underlie memory. Epigenetic modifications of DNA and chromatin struct

• WM-8014 br Histamine H R The cloning of the H

  2022-07-05

  

  Histamine H4R The cloning of the H3R (Lovenberg et al., 1999) provided a template for the search of other WM-8014 receptors, and resulted in the most recent discovery of histamine H4R. This concluded with six independent groups that have reported the cloning of the H4R (Leurs et al., 2009, Liu et

• Taken together this study provides the proof of concept that

  2022-07-04

  

  Taken together, this study provides the proof of concept that our novel heterologous human/rat HER2-specific T cell vaccine HuRt-TEXO, which is capable of stimulating both humoral and CTL responses leading to potent antitumor immunity through the circumvention of HER2 tolerance in double transgenic

• Small but statistically significant variance in PhyChem inde

  2022-07-04

  

  Small but statistically significant variance in 7 PhyChem indexes measured using intra-host HVR1 variants was shown to be strongly associated with CIP and MIP. All HVR1 sequences (N = 28,622) used here share only 6782 profiles of the selected 29 DAC’ of 7 PhyChem indexes. The significant majority (9

• br S proteins and HBV induced autophagy

  2022-07-04

  

  S proteins and HBV-induced autophagy HBV surface proteins (S proteins or HBs) are reported to trigger HBV-induced autophagy by inducing ER stress and UPR in host Dehydrocostus Lactone [22]. HBx and HBV-induced autophagy HBx is a multifunctional viral protein. It can regulate virus replicatio

• The haspin gene is also

  2022-07-04

  

  The haspin gene is also unusual because it lacks introns. This is more remarkable when one compares the mammalian genes to those of likely haspin orthologs that are present in the genomic sequences of other species. Such genes in Drosophilamelagonaster, Arabidopsisthaliana and Caenorhabditiselegans

• br Conclusion B esterases and reproductive parameters

  2022-07-04

  

  Conclusion B-esterases and reproductive parameters can be used as effect biomarkers of the aquatic contamination with chlorpyrifos. In P. corneus exposed for 14 days to the insecticide, the carboxylesterases determined with p-NFB proved to be the most sensitive biomarker. However, exposure to env

• In conclusion our results show that

  2022-07-04

  

  In conclusion, our results show that P7C3 enhances endogenous neurogenesis by upregulating the generation of endogenous neuroblasts and neural stem/progenitor cells by increasing the expression of neuroprotective proteins (Bcl-2, ki67, DCX, adam11, adamts20, and β-tub3) by activation of the cAMP/PKA

• Finally our work showed that HAART resulted in

  2022-07-04

  

  Finally, our work showed that HAART resulted in significant inter-individual variability among DEGs, which reflected the Sorbitol in HIV-affected human gene expressions (Fig. 1, Fig. 2, Fig. 3, Fig. 4). These observations also highlighted the importance of determining common as well as personal spec

• To date no studies have demonstrated

  2022-07-04

  

  To date, no studies have demonstrated any effect of obesity or inflammation on GPR109A expression in adipose tissue. Our findings demonstrate that HFD-induced obesity decreases adipose tissue GPR109A gene expression. Contradictory to our findings in adipose tissue in vivo, Digby et al. report that e

14465 records 388/965 page Previous Next First page 上5页 386387388389390 下5页 Last page