Archives
- 2018-07
- 2019-08
- 2019-09
- 2019-10
- 2019-11
- 2019-12
- 2020-01
- 2020-02
- 2020-03
- 2020-04
- 2020-05
- 2020-06
- 2020-07
- 2020-08
- 2020-09
- 2020-10
- 2020-11
- 2020-12
- 2021-01
- 2021-02
- 2021-03
- 2021-04
- 2021-05
- 2021-06
- 2021-07
- 2021-08
- 2021-09
- 2021-10
- 2021-11
- 2021-12
- 2022-01
- 2022-02
- 2022-03
- 2022-04
- 2022-05
- 2022-06
- 2022-07
- 2022-08
- 2022-09
- 2022-10
- 2022-11
- 2022-12
- 2023-01
- 2023-02
- 2023-03
- 2023-04
- 2023-05
- 2023-06
- 2023-07
- 2023-08
- 2023-09
- 2023-10
- 2023-11
- 2023-12
- 2024-01
- 2024-02
- 2024-03
- 2024-04
- 2024-05
- 2024-06
- 2024-07
- 2024-08
- 2024-09
- 2024-10
-
Channeling of SFA away from generation of toxic
2022-05-21
Channeling of SFA away from generation of toxic lipid metabolites such as ceramide, towards inert TG accumulation in response to cosupplementation with increased levels of MUFAs has previously been shown in many cell types including the pancreatic β-cells [37]. Our studies indicate that similar mech
-
The other type of cell death that occurs
2022-05-20
The other type of cell death that occurs in activated T epacadostat is caused by growth factor withdrawal following TCR-mediated activation, whereby most of the activated T cells die by apoptosis following the eradication of bacteria during an acute infection in order to reduce the level of cytokin
-
br Problem of cellular retention not only affects the cellul
2022-05-20
Problem of cellular retention not only affects the cellular activity of the nanoparticles and nanocomplexes but can also have ramifications in their in vivo applications. While inorganic nanoparticles are being developed extensively for detection as well as treatment of different human diseases, i
-
The first phase of insulin secretion is
2022-05-20
The first phase of insulin secretion is due to calcium signaling because of glucose sensing, increased cytoplasmic ATP levels, cellular depolarization, calcium influx and activation of calcium sensing molecules that eventually causes the fusion of the insulin granules to plasma membrane (exocytosis
-
br Introduction Stroke is the
2022-05-20
Introduction Stroke is the second cause of death worldwide and the first cause of acquired motor disability in adults [1], [2]. In sub-Saharan Africa, stroke is the first cause of admission in neurology departments [3]. In Cameroon, the in-hospital mortality of stroke is estimated at 26.8% [4]. A
-
Experimental conditions may be critical to
2022-05-20
Experimental conditions may be critical to explain one model or the other. The matter of Hippo-driven cytoplasmic sequestration (Varelas et al., 2008) of active SMAD complexes (Varelas et al., 2008) vs. TßR basolateral relocalization upon epithelial polarization (Nallet-Staub et al., 2015) as mechan
-
A two way chi square test was used to determine
2022-05-20
A two-way chi-square test was used to determine statistically significant differences between corresponding frequencies of GT results for the 2 testing periods. A p value of Results Distribution of HCV GT results obtained during the 2 study periods are shown in Table 1. While very low frequencies
-
miRNAs post transcriptionally regulate gene expression by cl
2022-05-20
miRNAs post-transcriptionally regulate gene Afuresertib receptor by cleaving mRNA or inhibiting translation of target gene transcripts. Vita analysis of HBV genome sequence suggested that miR-185-5p may not directly act on HBV mRNAs, which suggested that miR-185-5p might suppress HBV gene expression
-
In human platelets only and isoforms of sGC are
2022-05-20
In human platelets, only α1 and β1 isoforms of sGC are expressed in equimolar concentrations (3700 copies for β1, and 3500 copies for α1 per platelet) [57] [62]. sGC, is usually a heterodimer and contains heme as cofactor which is required for high-affinity NO binding and stimulation of its activity
-
br TGR agonists current developments and future landscape
2022-05-20
TGR5 agonists: current developments and future landscape The amphipathic nature of bile acids is crucial in aiding the digestion and TC-I 15 of vitamins and fats. With the emerging roles of bile acids in the regulation of energy and glucose homeostasis through TGR5, the pharmaceutical industry ha
-
br Acknowledgements We thank the support of
2022-05-20
Acknowledgements We thank the support of the National Natural Science Foundation of China (NSFC) project 81501342 and support from the Disciplinary Group of Oncology and Immunology program of Xinxiang Medical University. Introduction First described as a new clinical entity in 1981, the Acqui
-
The amino hydroxy methyl isoxazolepropionic
2022-05-19
The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic MRT68921 australia (AMPA) receptors are related ionotropic glutamate receptors (iGluRs) that mediate fast excitatory neurotransmission, and are also typically heteromeric ion channels, composed of GluA2 subunits in conjugation with GluA1, GluA3, o
-
Although most of the incretin effects
2022-05-19
Although most of the incretin effects on terazosin hydrochloride metabolism can be secondary to their action on insulin/glucagon secretion, some evidence strongly suggests that they could also act directly on liver glucose utilization and production [4], [13], [22], [27], [34], [44]. Supporting thi
-
Sequences of hexokinases were initially deduced
2022-05-19
Sequences of hexokinases were initially deduced and predicted based on cDNA clones (Andreone et al., 1989, Schwab and Wilson, 1989, Schwab and Wilson, 1991, Griffin et al., 1991, Thelen and Wilson, 1991). Analysis of genome sequence data identified, in Risperidone to the 4 expected known hexokinase
-
Nemonapride br Introduction Glucose homeostasis is primarily
2022-05-19
Introduction Glucose homeostasis is primarily regulated by the hormones insulin and glucagon, secreted from the pancreatic islets of Langerhans. Although insulin produced by β Nemonapride is the blood glucose-lowering hormone, glucagon secreted from α cells acts as the major counter-regulatory h
13460 records 351/898 page Previous Next First page 上5页 351352353354355 下5页 Last page