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br Epidemiology br Genetics The dominantly inherited PrP cer
2022-10-13
Epidemiology Genetics The dominantly inherited PrP cerebral amyloidoses are genetically transmitted with a penetrance of almost 100%. Early linkage analysis studies helped to established the relationship between GSS and mutations in the PRNP gene. PRNP is located on the short arm of chromosome
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br Conclusions br Introduction In the modern
2022-10-13
Conclusions Introduction In the modern life of humans, Parthenolide are widely prescribed for therapy against bacterial diseases to prevent the onset of bacterial infections during a viral disease (Goossens et al., 2005; Van Boeckel et al., 2014). They have been massively administered and per
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To our knowledge this study collected all
2022-10-13
To our knowledge, this study collected all published research of occurrence of 9090 in water, sediment and aquatic organisms of typical Lakes by 2017 according to http://www.cnki.net/, https://xue.glgoo.net/, http://xueshu.baidu.com/, and http://www.sciencedirect.com/. Some information of Lakes are
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Based upon these findings the S lipoxygenase seems to
2022-10-13
Based upon these findings, the 12S-lipoxygenase seems to increase membrane excitability by specifically inhibiting M-type K+ channels. The 12S-lipoxygenase is expressed in many parts of mammalian abt 737 including the cerebrum, cerebellum, hypothalamus, basal ganglia, hippocampus, olfactory bulb, a
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abiraterone acetate br Conclusion br Acknowledgement This st
2022-10-13
Conclusion Acknowledgement This study was supported by NIH/NINDSR01 NS036812-16. Introduction Lipoxygenases (LOXs) are a heterogeneous family of enzymes that catalyze the peroxidation of polyunsaturated fatty acids (PUFAs). By oxidizing free PUFAs, they were shown to contribute to the gene
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br Conclusions br Conflict of interest br Introduction Plant
2022-10-13
Conclusions Conflict of interest Introduction Plants often encounter a series of abiotic stresses during the growth process, including high salinity, extreme temperatures and drought (Knight and Knight, 2001). Plants can adapt through ionic and osmotic homeostasis or osmotic adjustment, con
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Search sphere This sphere includes the acetylcholine binding
2022-10-13
Search sphere 1: This sphere includes the INT-777 binding site between the α–γ subunits. The center point of the search area was located at x=35.26, y=77.67, z=137.74 and the initial search radius was set to 27Å which assures that the corresponding area outside the channel pore of the two subunits
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br Experimental br Acknowledgements This work was financiall
2022-10-12
Experimental Acknowledgements This work was financially supported by Ministry of Knowledge and Economy (10032113) and Ministry of Education, Science and Technology (20100000297). Introduction To ensure accurate chromosome segregation, cohesion between sister chromatids must be maintained u
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We have shown previously that activation
2022-10-12
We have shown previously that activation of the TGFβ/Smad signaling pathway in keratinocytes regulates Hydroxyurea cytoskeleton organization via non-genomic and genomic mechanisms and that RhoB gene is a target of Smad proteins [12,13]. Although the role of RhoB in early non-genomic TGFβ-induced cel
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br Materials and methods br Results
2022-10-12
Materials and methods Results As expected, due to matching by age, the mean ages were similar for the two groups of children when stratified by ASD status; children with an ASD had a mean age of 67.0 months, while the mean age for children in the TD control group was 68.0 months. Nearly all of
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GSTP c C T SNP
2022-10-12
GSTP1 c.341C > T SNP was genotyped in 90 patients tumor and 180 normal healthy individuals. The profile of GSTP1 c.341C > T Acitretin and genotypes is shown in Table 2. The profile of the genotypes was in agreement with Hardy-Weinberg equilibrium (χ2 = 2.11). Minor allele frequency (341T) among OSC
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Among the symbiotic bacteria contained in the probiotics
2022-10-12
Among the symbiotic bacteria contained in the probiotics, lactic-acid-producing bacteria (LAB) have been suggested to confer broad spectrums of health benefits, such as activation of mucosal and systemic immunity and resistance to infectious illnesses (Schiffrin et al., 1995, Wells and Mercenier, 20
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br Endogenous and synthetic ligands
2022-10-12
Endogenous and synthetic ligands of GPR55 There are currently limited commercially available synthetic agonists and antagonists that are specific for GPR55. A large number of studies have investigated the pharmacology of GPR55 4, 23, 25, 30, 31, 32, 33, 34, 35, with contradictory findings reporte
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br A selective inhibitor of mammalian histone deacetylase tr
2022-10-12
A selective inhibitor of mammalian histone deacetylase, trichostatin A, reduces GnRH mRNA expression Epigenetic mechanisms controlling GnRH expression have been reported, and these mechanisms may be involved in the development and maturation of GnRH neurons in the brain (Gan et al., 2012, Kurian
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br The glycine transporter GlyT was
2022-10-12
The glycine transporter 1 (GlyT1) was originally identified as a member of the solute carrier family 6 of sodium- and chloride-dependent neurotransmitter transporters . GlyT1 is expressed in the central nervous system and in peripheral tissues; mainly in erythroid cells, from erythroblasts in the
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